Posts Tagged ‘Aplastic Anemia’

Jul

Are There Any Support Groups For Aplastic Anemia? If There Are Where?

anemia is a disease. the one i am finding is aplastic anemia.
are ther any support groups for apalstic anemia? i need just a few doesn’t mattter where.

Jul

I Have Aplastic Anemia And Was Looking For Some Help From Anyone Out There.?

i have been diagnosed with aplastic anemia and i was just wondering if there was anyone else who could maybe help me out.. i was wondering what the blood cell count would be for someone who had a serious case as to a moderate case and what the doses of certain prescriptions would be. Just wanting to know exactly how serious mine is considering my family is my doctor so its a little hard to tell. anything would help!

Jul

Why Is There No Splenomegaly In Aplastic Anemia? If Low Rbcs, Shouldn’t There Be Extramedullary Hematopoesis?

and if the spleen performs the extramedullary hematopoesis, shouldn’t it enlarge? So, why is there no splenomegaly in aplastic anemia? Please enlighten me. Thanks!

Jul

Any Parents Dealing With Aplastic Anemia?

My 7 1/2 year old son has been undergoing treatment for Aplastic Anemia for the past 6 months. I need to know that there is a light at the end of the tunnel. Has anyone been through this?

Jul

Aplastic Anemia And Bone Marrow Transplant?

Hi my name is Sarah, im 19, live in Ballina Australia, and im trying to find anyone that has had aplastic anemia and a bone marrow transplant like me!

Jul

Was Marie Curie Diagnosed With Aplastic Anemia Before Her Death?

I want to know if she knew of the ailment before she passed. If so, how long did she know?

Jul

Aplastic Anemia, Side Affects Later In Life With Pregnancy And Being Fertile?

my girl has aplastic anemia, she got past it. the only info her doctor gave her was saying she might have problems having children when she is older.
anyone know if you are less fertile after having aplastic anemia? is that what the doctor meant, that it damaged her whole ordeal with being fertile enough to concieve?

Jul

Can Stress Be A Cause To Get Aplastic Anemia?

I’ve asked this yesterday and got nothing yet. So I thought I’ve rephrased it. Other than blood cells, can stress bring it on and cause it to happen? Any health professionals out there?

Jul

Radium Girls: Women spirit

The case described in this article is historical in many ways especially in the fields of health physics and the labor rights movement. The whole case revolves around the United States Radium Corporation. Founded in 1914 in Newark, New Jersey, this company produced uranium from carnotite ore and later moved into the business of producing radioluminescent paint Undark. They began to hire workers around 1917, mostly women, whose job was to paint watches with special glow-in-the-dark paint, where radium was one of the ingredients. The women were told that the paint was harmless and even encouraged to sharpen the brushes they used during work to with their tongues and fingers. Unaware of the danger some of the girls even painted their fingernails, faces and teeth, to surprise their boyfriends in the dark or just for fun. Naturally the girls received huge doses of radiation, which led to bone diseases and ultimately deaths. It is important to note that the owners and their scientists were familiar with the effects of radium and avoided the dangerous chemical with lead screens, masks and tongs. After a certain period of time many of the women began to suffer from fractures and necrosis of the jaw (later named the Radium Jaw condition). The United States Radium Corporation and some other watch-dial companies denied the fact that the compound used to paint watches was radioactive and rejected the claims, stating that the medical issues appeared from other medical conditions. Doctors, dentists, and researchers who were working on the radium cases received requests from the companies not to release their data.

In 1925 the chief medical examiner of Essex County, New Jersey published a report that stated that the cause of bone disease and aplastic anemia, and deaths of the workers was radium. Five of the survived woman sued their employer in a historical case that later established the right of individual workers who contract occupational diseases to sue their employers for this. The first worker who decided to sue was Grace Fryer, but it took her two years to find a lawyer that would take on U.S. Radium. Eventually she found one and was joined by four more ill workers. The whole case received a lot of media attention and so it became impossible to deny the true facts. This triggered big changes in the governing labor safety standards. The United States Radium was closed in 1927, mostly because of this legal case. The case itself was settled out of court in 1928. The company was considered to take too much time for settling the case intentionally, because most of the workers were too ill to survive and receive compensation. The settlement for each of the girls was $10,000 and a $600 per year annuity while they lived, plus coverage of all the medical and legal expenses.

The Radium Girls became a well known case and was referenced in many books and movies. The contamination was so serious that even today the graves of the workers can be detected with Geiger counter.

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Jul

Acetohexamide Drug (medication) Information

Acetohexamide is used in adjunctive therapy, used with dietary modification, in patients with noninsulin-dependent diabetes mellitus (type II) for lowering blood glucose level.

How to Take Acetohexamide

Take Acetohexamide exactly as prescribed by health care provider. Acetohexamide is avaliable in form of Tablets 250 mg, Tablets 500 mg.

Dosage Instructions for Acetohexamide Drug

Adults: PO 325 to 650 mg prn q 4 to 6 hr or 1 g 3 to 4 times/day. Do not exceed 4 g/day.

Children: PO 10 to 15 mg/kg dose prn q 4 to 6 hr; do not exceed 5 doses/24 hr.

Contraindications of Acetohexamide

Hypersensitivity to sulfonylureas; diabetes complicated by ketoacidosis; sole therapy of insulin-dependent (type I) diabetes mellitus; diabetes complicated by pregnancy.

Interactions of Acetohexamide with other drugs

Androgens, chloramphenicol, clofibrate, fenfluramine, H 2 antagonists, MAOIs, phenylbutazone, probenecid, salicylates, sulfonamides: Hypoglycemic effect may be increased.

Diazoxide, rifampin, thiazide diuretics: Hypoglycemic effect of acetohexamide may be decreased.

What are the Side Effects of Acetohexamide -

Like other medicines, Acetohexamide can cause side effects. Some of the more common side effects of Acetohexamide include

* Possible increased risk of cardiovascular mortality as compared with treatment with diet alone.

* Dizziness; vertigo.

* Allergic skin reactions; eczema; pruritus; erythema; urticaria; morbilliform or maculopapular eruptions, lichenoid reactions; photosensitivity.

* Nausea; epigastric fullness; heartburn; cholestatic jaundice (rare, discontinue drug if this occurs).

* Mild diuresis.

* Leukopenia; thrombocytopenia; aplastic anemia; agranulocytosis; hemolytic anemia; pancytopenia.

* Disulfiram-like reaction; weakness; paresthesia, fatigue; malaise.

Warnings and precautions before taking Acetohexamide :

* Assess current blood glucose levels. Observe patient for signs of hyperglycemia (eg, frequent urination, thirst, weakness, weight loss, ketoacidosis) and hypoglycemia (eg, tingling of lips and tongue, nausea, diminished cerebral function [eg, lethargy, confusion], tachycardia, sweating, convulsions, coma). Have oral glucose or carbohydrates and IV glucose available.

* Monitor effectiveness of diabetes control through individualized treatment plan, including diet, daily blood glucose levels, medication, and exercise.

* The safety and efficay of Acetohexamide medicine have not been studied in children and adolescents.

* Instruct patient to call health care provider if any of the following symptoms occur: nausea, vomiting, heartburn, diarrhea, fever, sore throat, rash, itching, weakness, unusual bruising, bleeding.

* Caution patient to avoid exposure to sunlight, and to use sunscreen or wear protective clothing to avoid photosensitivity reaction.

* Advise women to inform health care provider if pregnant, planning to become pregnant, or breastfeeding while taking Acetohexamide. Insulin is recommended to maintain blood glucose levels during pregnancy. Prolonged severe neonatal hypoglycemia can occur if sulfonylureas are administered at time of delivery.

What if Overdose of Acetohexamide ?

If you think you or anyone else taken overdose of Acetohexamide , immediately telephone your doctor or contact your local or regional Poisons Information Centre Seek medical attention immediately. You may need urgent medical attention. Hypoglycemia, mild hypoglycemia without loss of consciousness and no neurologic findings, severe hypoglycemic reactions may be a sign of overdose of Acetohexamide.

What if Missed Dose of Acetohexamide ?

If you miss a dose of Acetohexamide medicine and you remember within an hour or so, take the dose immediately. If you do not remember until later, skip the dose you missed and go back to your regular schedule. Do not double doses.

Storage Conditions for Acetohexamide :

Store tablets and powder for injection at ambient room temperature (59° to 86°F). Store Acetohexamide reconstituted injectable solution in refrigerator (36° to 46°F) for up to 3 days or use within 12 hr of reconstitution if stored at room temperature (59° to 86°F).

By: ashu

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Jul

aplastic anemia symptoms

Aplastic Anemia being a rare disease has led to many deaths often thanks to lack of early diagnosis. However, if the indications of the disease are discovered sufficiently early, it is possible to either control or cure the disease completely. Just like any other disease, the severity of the condition determines the type of treatment to be undertaken. Cases of Aplastic Anemia may be serious, mild or moderate. Serious Aplastic Anemia requires that the patient be hospitalised for specialized treatment as it is life-threatening. These treatments can either be used with an aim of managing the disease for a considerable time or to totally cure the disease.aplastic anemia symptomsBlood transfusion as an example does not cure the disease and multiple blood transfusions might be needed to provide the desperately required blood cells that the bone marrow is not able to provide. The use of a growth factor may however be considered to help the body produce more blood cells to reduce the amount of transfusions. A bone marrow transplant will most likely require that the patient discovers a bone marrow donor, generally a close relative or a not related but matching donor. A likely risk in this type of treatment is where the patient’s system rejects the transplant which may lead to serious problems. Immunosuppresants are used where the body immune mechanism is the one attacking cells produced in the bone marrow. This treatment acts by suppressing the immune system. The disadvantage of these drugs is that they may weaken the patient’s immune system and in case the patient stops use their conditions are likely to recur. Other methods used for containing the problem include the use of bone marrow stimulants and the use of anti-retrovirals and antibiotics.This medication is widely known for its low relapse rate and fewer side effects as opposed to other types of chemotherapy and Aplastic Anemia treatments. Cytoxan is also used to refer to Cyclophosphamide which is essentially a brandless name. Patients who receive this treatment have to mix it with GCSF which is a growth factor. The Cytoxan gets rid of the lymphocytes while leaving the healthy stem cells untouched. The bone marrow can then start manufacturing new healthy cells for the body at the normal rate.Read more at aplastic anemia symptoms

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Jul

Aplastic Anemia Treatment

Aplastic Anemia being a rare illness has led to many deaths mostly thanks lack of early diagnosis. However, if the indicators of the illness are discovered early enough, it is feasible to either control or cure the illness completely. Just like every other illness, the scale of the condition determines the kind of treatment to be undertaken. Severe Aplastic Anemia specifies that the patient be hospitalized for specialized treatment as it is potentially fatal. In the primary stages of treatment, the patient might have to undergo blood transfusion as he awaits treatment. Different techniques of treating Aplastic Anemia are available though the most typically known standard strategies are blood transfusion, bone marrow transplant and Immunosuppressive therapy. These treatments can either be used with a purpose of handling the illness for a substantial time or to completely cure the disease.
Aplastic Anemia Treatment
Bone Marrow transplant is understood to cure Aplastic Anemia and recurrence is generally restricted to one out of 5 cases. A likely risk in this sort of treatment is where the patient’s system rejects the transplant which may lead to serious problems. Immunosuppresants are used where the body immune mechanism is the one attacking cells produced in the bone marrow. Examples of gear used as immunosuppressants are anti-thymocyte globulin and clysporine. The drawback of these drugs is that they may weaken the patient’s immune system and in case the patient stops use their conditions are probably going to reappear.
Research on Aplastic Anemia is still going on to come up with better treatments for the illness. High-Dose Cyclophosphamide is among the latest treatment for Aplastic Anemia in the market which is still being used in controlled trial. Cytoxan is also used to refer to Cyclophosphamide which is basically a common name. Patients who receive this treatment have to mix it with GCSF which is an expansion factor. The Cytoxan gets rid of the lymphocytes while leaving the healthy stem cells untouched. The bone marrow can then start manufacturing new healthy cells for the body at the ordinary rate.
Read more at Aplastic Anemia Treatment

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